We believe that the UK should allow the compassionate use of non-GMP phages produced in the UK for last resort medical cases where other medical approaches have failed or are failing. This would bring the UK in line with several EU countries, and the USA and Australia. The UK can learn from these countries in ensuring that phages are produced to a high standard, albeit not to the exacting standard of GMP. Using monographs, as is the case in Belgium, that stipulate safety and purity standards, would be an ideal starting place. It could build upon existing guidance for the use of unlicensed specials (products that have not been assessed by the regulatory authority for safety, quality and efficacy in the same way as licensed products) within UK clinical settings and oversight procedures within hospitals. (Paragraph 128) 62 The antimicrobial potential of bacteriophages