The diagnosis of ectopic pregnancy

HSIB Legacy Published
Published 14 October 2022 · Launched 18 October 2018
Emergency care Communication and decision making

An estimated 12,000 women experience an ectopic pregnancy each year in the UK. Ectopic pregnancy occurs when the fertilised egg implants outside the uterus, usually in the Fallopian tube. If it’s left untreated, it can rupture and cause internal bleeding.

4 recommendations
2 observations
3 of 4 responded

Safety Recommendations (4)

Royal College of Emergency Medicine (‘RCEM’) R/2020/076
It is recommended that the Royal College of Emergency Medicine should provide standardised discharge information for clinicians to offer to women following discharge from the emergency department with a problem in early pregnancy and while awaiting further assessment by early pregnancy services.
RCEM accepts the recommendation and will develop a standardised patient leaflet template for discharge advice on early pregnancy problems, making it available on their website along with a safety flash.
The Royal College of Emergency Medicine (RCEM) is happy to accept the safety recommendation made by HSIB. The RCEM will be developing a patient leaflet template to be made available on the RCEM website. The template will form the basis for a discharge advice leaflet. Clinicians can offer the leaflet to women who have been discharged from emergency departments after experiencing a problem in early pregnancy and who need to attend an early pregnancy service at a later date. Clinicians can adapt the template to reflect their local service arrangements and include relevant details of their local departments. In addition to the leaflet template, the RCEM will be releasing a safety flash that will reference the event from the HSIB investigation as well as a link to the HSIB report. The safety flash will also include a link to the RCEM leaflet template and RCEM recommendations on important information to be included in the discharge leaflet. Response received on 6 January 2021.
Royal College of Obstetricians and Gynaecologists R/2020/077
It is recommended that the Royal College of Obstetricians and Gynaecologists should provide guidance on the information that should be provided during referral to early pregnancy units to standardise and improve the flow of information required to identify those most at risk from ectopic pregnancy and any consequent deterioration
RCOG will incorporate guidance on information required for early pregnancy unit referrals into their updated Green-top Guideline on Ectopic Pregnancy, which is expected to be published in 2023.
We were very concerned to hear about any missed ectopic pregnancy as the complications are very serious and can be life threatening. Early diagnosis and treatment is crucial, and more could be done to improve early detection methods and raise awareness of the symptoms so women and their clinicians can recognise that something is wrong as soon as possible. It is also essential that information between health professionals is shared in a streamlined and efficient fashion during referral to early pregnancy units so action can be taken swiftly. We acknowledge HSIB’s safety recommendation in the report and we will include it in the next update of our guidance which is currently underway. We will also work with the Royal College of Emergency Medicine to ensure consistency of approach across all acute settings. Symptoms of ectopic pregnancy can include vaginal bleeding, abdominal pain, shoulder tip pain and discomfort going to the toilet. Women presenting with these symptoms and a positive pregnancy test should be offered referral to a local early pregnancy unit for ongoing care. We have information for women and their families about ectopic pregnancy on our website, including symptoms, when to seek advice, risks and diagnosis and treatment options. The information is also available in a print and audio leaflet. We are updating the RCOG Green-top Guideline (no 21) on the Diagnosis and Management of Ectopic Pregnancy to include the information that should be provided during referral to early pregnancy units. This information standardises and improves the flow of information required to identify those most at risk from ectopic pregnancy and any consequent deterioration. It is expected the guideline will be published during 2023. Response received on 16 December 2021.
CQC R/2020/078
It is recommended that the Care Quality Commission Services Framework for Gynaecology and Termination Services includes an assessment of early pregnancy services, using as a reference the National Institute for Health and Care Excellence Guideline 126, Ectopic pregnancy and miscarriage: diagnosis and initial management.
CQC fully supports the recommendation to include early pregnancy service assessment in their framework, but implementation planned for April 2020 was delayed by COVID-19 and will be incorporated into a "future framework."
CQC fully supports HSIB’s safety recommendations. Implementation was planned for April 2020. This work has been delayed by the impact of the Covid-19 but this important recommendation will be brought into our future framework. Response received on 10 September 2020.
R/2020/075
The National Institute for Health and Care Excellence should review and revise the clinical knowledge summary for ‘urinary tract infection (lower) – women’ to include ectopic pregnancy as a category under ‘alternative or serious diagnoses’.
No response published on HSSIB's website

Safety Observations (2)

There is insufficient capacity to meet the demand for sonography if early pregnancy units are to deliver a seven-day-a-week service. It may be beneficial for NHS England/Improvement and Health Education England to carry out a workforce review to identify a strategy to meet this demand.
Care providers may benefit from conducting a proactive systematic risk analysis when designing or reviewing care pathways. Such an analysis should consider ‘work as done’ (the way work is actually carried out, which may differ from written policies and procedures) in order to identify and mitigate hazards that impact patient safety Glossary of abbreviations Glossary of abbreviations CASE Consortium for the Accreditation of Sonographic Education CNS clinical nurse specialist CQC Care Quality Commission ED emergency department ENP emergency nurse practitioner EPU early pregnancy unit EWS early warning score GMC General Medical Council Hb haemoglobin hCG human chorionic gonadotrophin HSIB Healthcare Safety Investigation Branch MIU minor injuries unit NICE National Institute for Health and Care Excellence OOH out of hours RCEM Royal College of Emergency Medicine RCOG Royal College of Obstetricians and Gynaecologists SCoR Society and College of Radiographers SMA subject matter advisor StEIS Strategic Executive Information System TVUS transvaginal ultrasound scan UTI urinary tract infection HRO high reliability organisation