MHRA Drug & Device Safety Alerts

Safety alerts, recalls, and field safety notices from the Medicines and Healthcare products Regulatory Agency — covering drug safety updates, medical device alerts, and class recalls.

514

Total Alerts

250

Drug Safety Updates

264

Device Alerts

Alerts by Type

Key Insights

514 MHRA alerts tracked. 250 Drug Safety Updates. 264 Medical Device Alerts.

MHRA alerts link to NHS trusts and healthcare bodies — cross-reference with responsible body scorecard pages to surface patterns between safety alert volumes and inquiry recommendation delivery.

Showing 514 alerts

Class 3 Medicines Recall: Activase Pharmaceuticals Limited, Prednisolone 5mg Soluble Tablets, EL(25)A/54

class-3-medicines-recall-activase-pharmaceuticals-limited-prednisolone-5mg-soluble-tablets-el-25-a-s Medical Device Alert

15 Dec 2025 MHRA

Class 2 Medicines Recall: Hameln Pharma Ltd, Clarithromycin 500 mg powder for concentrate for solution for infusion, EL…

class-2-medicines-recall-hameln-pharma-ltd-clarithromycin-500-mg-powder-for-concentrate-for-solution Medical Device Alert

11 Dec 2025 MHRA

Class 4 Medicines Defect Notification: Flamingo Pharma UK Ltd, Amitriptyline Hydrochloride 10mg, 25mg, 50mg Tablets, EL…

class-4-medicines-defect-notification-flamingo-pharma-uk-ltd-amitriptyline-hydrochloride-10mg-25mg-5 Medical Device Alert

10 Dec 2025 MHRA

Field Safety Notices: 1 to 5 December 2025

field-safety-notices-1-to-5-november-2025 Medical Device Alert

08 Dec 2025 MHRA

Mesalazine and idiopathic intracranial hypertension

mesalazine-and-idiopathic-intracranial-hypertension Drug Safety

04 Dec 2025 MHRA

Field Safety Notices: 24 to 28 November 2025

field-safety-notices-24-to-28-november-2025 Medical Device Alert

02 Dec 2025 MHRA

Class 4 Medicines Defect Notification: Special Concept Development UK Limited, Baclofen 10mg Tablets, EL(25)A/51

class-4-medicines-defect-notification-special-concept-development-uk-limited-baclofen-10mg-tablets-e Medical Device Alert

27 Nov 2025 MHRA

MHRA Safety Roundup: November 2025

mhra-safety-roundup-november-2025 Medical Device Alert

27 Nov 2025 MHRA

Class 4 Medicines Defect Notification: Lexon UK Ltd, Moclobemide 150mg tablets, EL(25)A/50

class-4-medicines-defect-notification-lexon-uk-ltd-moclobemide-150mg-tablets-el-25-a-slash-50 Medical Device Alert

25 Nov 2025 MHRA

Field Safety Notices: 17 to 21 November 2025

field-safety-notices-17-to-21-november-2025 Medical Device Alert

25 Nov 2025 MHRA

Field Safety Notices: 10 to 14 November 2025

field-safety-notices-10-to-14-november-2025 Medical Device Alert

24 Nov 2025 MHRA

Class 3 Medicines Recall: Sun Pharmaceutical Industries Limited, Fingolimod SUN 0.5mg hard capsules, EL(25)A/49

class-3-medicines-recall-sun-pharmaceutical-industries-limited-fingolimod-sun-0-dot-5mg-hard-capsule Medical Device Alert

20 Nov 2025 MHRA

Class 3 Medicines Recall: Sun Pharmaceutical Industries Limited, Atorvastatin 20mg and 80mg Film-coated Tablets, EL(25)…

class-3-medicines-recall-sun-pharmaceutical-industries-limited-atorvastatin-20mg-and-80mg-film-coate Medical Device Alert

11 Nov 2025 MHRA

Field Safety Notices: 3 to 7 November 2025

field-safety-notices-3-to-7-november-2025 Medical Device Alert

11 Nov 2025 MHRA

Class 3 Medicines Recall: Zambon SpA, Emylif 50mg orodispersible film, EL(25)A/47

class-3-medicines-recall-zambon-spa-emylif-50mg-orodispersible-film-el-25-a-slash-47 Medical Device Alert

10 Nov 2025 MHRA

Field Safety Notices: 27 to 31 October 2025

field-safety-notices-27-to-31-october-2025 Medical Device Alert

04 Nov 2025 MHRA

Field Safety Notices: 11 to 15 August 2025

field-safety-notices-11-to-15-august-2025 Medical Device Alert

28 Oct 2025 MHRA

MHRA Safety Roundup: October 2025

mhra-safety-roundup-october-2025 Medical Device Alert

28 Oct 2025 MHRA

Field Safety Notices: 20 to 24 October 2025

field-safety-notices-20-to-24-october-2025 Medical Device Alert

28 Oct 2025 MHRA

Class 2 Medicines Recall: Baxter Healthcare Limited, Compound Sodium Lactate Solution for Infusion BP (Hartmann's Solut…

class-2-medicines-recall-baxter-healthcare-limited-compound-sodium-lactate-solution-for-infusion-bp- Medical Device Alert

28 Oct 2025 MHRA

Isotretinoin – updates to prescribing guidance and survey of services

isotretinoin-updates-to-prescribing-guidance-and-survey-of-services Drug Safety

27 Oct 2025 MHRA

#MedSafetyWeek (3-9 November 2025): A call to action to improve patient safety

number-medsafetyweek-3-9-november-2025-a-call-to-action-to-improve-patient-safety Drug Safety

23 Oct 2025 MHRA

Class 3 Medicines Recall: Accord Healthcare Ltd, Ipratropium Bromide 500 microgram / 2ml Nebuliser Solution, EL(25)A/45

class-3-medicines-recall-accord-healthcare-ltd-ipratropium-bromide-500-microgram-slash-2ml-nebuliser Medical Device Alert

23 Oct 2025 MHRA

Class 4 Medicines Defect Notification: Relonchem Ltd, Various Products, EL(25)A/44

class-4-medicines-defect-notification-relonchem-ltd-various-products-el-25-a-slash-44 Medical Device Alert

23 Oct 2025 MHRA

Field Safety Notices: 13 to 17 October 2025

field-safety-notices-13-to-17-october-2025 Medical Device Alert

21 Oct 2025 MHRA

Field Safety Notices: 6 October to 10 October 2025

field-safety-notices-6-october-to-10-october-2025 Medical Device Alert

14 Oct 2025 MHRA

Field Safety Notices: 29 September to 3 October 2025

field-safety-notices-29-september-to-3-october-2025 Medical Device Alert

07 Oct 2025 MHRA

BD BodyComm™ version 3.3 software used for BodyGuard infusion pumps, BodyGuard-T and T34 syringe drivers: Important ste…

bd-bodycomm-version-3-dot-3-software-used-for-bodyguard-infusion-pumps-bodyguard-t-and-t34-syringe-d Medical Device Alert

06 Oct 2025 MHRA

Field Safety Notices: 22 to 26 September 2025

field-safety-notices-22-to-26-september-2025 Medical Device Alert

30 Sep 2025 MHRA

MHRA Safety Roundup: September 2025

mhra-safety-roundup-september-2025 Medical Device Alert

30 Sep 2025 MHRA

Field Safety Notices: 15 to 19 September 2025

field-safety-notices-15-to-19-september-2025 Medical Device Alert

23 Sep 2025 MHRA

Paracetamol and pregnancy - reminder that taking paracetamol during pregnancy remains safe

paracetamol-and-pregnancy-reminder-that-taking-paracetamol-during-pregnancy-remains-safe Drug Safety

23 Sep 2025 MHRA

Field Safety Notices: 8 to 12 September 2025

field-safety-notices-8-to-12-september-2025 Medical Device Alert

17 Sep 2025 MHRA

Field Safety Notices: 1 to 5 September 2025

field-safety-notices-1-to-5-september-2025 Medical Device Alert

09 Sep 2025 MHRA

Class 4 Medicines Defect Notification: Hikma Farmacêutica, Gemcitabine 2g/52.6ml concentrate for solution for infusion,…

class-4-medicines-defect-notification-hikma-farmaceutica-gemcitabine-2g-slash-52-dot-6ml-concentrate Medical Device Alert

04 Sep 2025 MHRA

Profemur Cobalt Chrome Modular Neck Hip Replacements: Higher than anticipated risk of revision surgery, metal-wear effe…

profemur-cobalt-chrome-modular-neck-hip-replacements-higher-than-anticipated-risk-of-revision-surger Medical Device Alert

04 Sep 2025 MHRA

Field Safety Notices: 25 to 29 August 2025

field-safety-notices-25-to-29-august-2025 Medical Device Alert

03 Sep 2025 MHRA

MHRA Safety Roundup: August 2025

mhra-safety-roundup-august-2025 Medical Device Alert

28 Aug 2025 MHRA

Class 4 Medicines Defect Notification: Ipca Laboratories UK Limited, Various Products, EL(25)A/42

class-4-medicines-defect-notification-ipca-laboratories-uk-limited-various-products-el-25-a-slash-42 Medical Device Alert

26 Aug 2025 MHRA

Field Safety Notices: 18 to 22 August 2025

field-safety-notices-18-to-22-august-2025 Medical Device Alert

26 Aug 2025 MHRA

Field Safety Notices: 5 to 9 May 2025

field-safety-notices-5-to-8-may-2025 Medical Device Alert

21 Aug 2025 MHRA

Class 4 Medicines Defect Notification: Fexofenadine Hydrochloride 120mg film-coated tablets, Chanelle Medical Unlimited…

class-4-medicines-defect-notification-fexofenadine-hydrochloride-120mg-film-coated-tablets-chanelle- Medical Device Alert

21 Aug 2025 MHRA

Class 4 Medicines Defect Notification: Levetiracetam Accord 100mg/ml oral solution, Accord Healthcare Limited, UK, EL(2…

class-4-medicines-defect-notification-levetiracetam-accord-100mg-slash-ml-oral-solution-accord-healt Medical Device Alert

14 Aug 2025 MHRA

Field Safety Notices: 4 to 8 August 2025

field-safety-notices-4-to-8-august-2025 Medical Device Alert

12 Aug 2025 MHRA

Class 4 Medicines Defect Notification: Topiramate Zydus Pharmaceuticals UK 20mg/ml Oral Solution, Zydus Pharmaceuticals…

class-4-medicines-defect-notification-topiramate-zydus-pharmaceuticals-uk-20mg-slash-ml-oral-solutio Medical Device Alert

07 Aug 2025 MHRA

Field Safety Notices: 28 July to 1 August 2025

field-safety-notices-28-july-to-1-august-2025 Medical Device Alert

05 Aug 2025 MHRA

Class 2 Medicines Recall: Fucidin 250 mg Tablets, LEO Laboratories Ltd trading as LEO Pharma, EL(25)A/38

class-2-medicines-recall-fucidin-250-mg-tablets-leo-laboratories-ltd-trading-as-leo-pharma-el-25-a-s Medical Device Alert

04 Aug 2025 MHRA

MHRA Safety Roundup: July 2025

mhra-safety-roundup-july-2025 Medical Device Alert

31 Jul 2025 MHRA

Class 4 Medicines Defect Notification: Olmesartan medoxomil 10mg film-coated tablets, Jubilant Pharmaceuticals NV, EL(2…

class-4-medicines-defect-notification-olmesartan-medoxomil-10mg-film-coated-tablets-jubilant-pharmac Medical Device Alert

31 Jul 2025 MHRA

Field Safety Notices: 21 to 25 July 2025

field-safety-notices-21-to-25-july-2025 Medical Device Alert

30 Jul 2025 MHRA