MHRA Drug & Device Safety Alerts

Safety alerts, recalls, and field safety notices from the Medicines and Healthcare products Regulatory Agency — covering drug safety updates, medical device alerts, and class recalls.

514
Total Alerts
250
Drug Safety Updates
264
Device Alerts

Alerts by Type

Key Insights

514 MHRA alerts tracked. 250 Drug Safety Updates. 264 Medical Device Alerts.

MHRA alerts link to NHS trusts and healthcare bodies — cross-reference with responsible body scorecard pages to surface patterns between safety alert volumes and inquiry recommendation delivery.

Showing 514 alerts

Omega-3-acid ethyl ester medicines (Omacor/Teromeg 1000mg capsules): dose-dependent increased risk of atrial fibrillati…
omega-3-acid-ethyl-ester-medicines-omacor-slash-teromeg-1000mg-capsules-dose-dependent-increased-ris Drug Safety
22 Jan 2024 MHRA
Fluoroquinolone antibiotics: must now only be prescribed when other commonly recommended antibiotics are inappropriate
fluoroquinolone-antibiotics-must-now-only-be-prescribed-when-other-commonly-recommended-antibiotics- Drug Safety
22 Jan 2024 MHRA
Vitamin B12 (hydroxocobalamin, cyanocobalamin): advise patients with known cobalt allergy to be vigilant for sensitivit…
vitamin-b12-hydroxocobalamin-cyanocobalamin-advise-patients-with-known-cobalt-allergy-to-be-vigilant Drug Safety
18 Dec 2023 MHRA
Aripiprazole (Abilify and generic brands): risk of pathological gambling
aripiprazole-abilify-and-generic-brands-risk-of-pathological-gambling Drug Safety
18 Dec 2023 MHRA
Letters and medicine recalls sent to healthcare professionals in November 2023
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-november-2023 Drug Safety
18 Dec 2023 MHRA
National Patient Safety Alert: Valproate: organisations to prepare for new regulatory measures for oversight of prescri…
national-patient-safety-alert-valproate-organisations-to-prepare-for-new-regulatory-measures-for-ove Medical Device Alert
28 Nov 2023 MHRA
Specific brands of carbomer eye gel: recall of AACARB eye gel, AACOMER eye gel and PUROPTICS eye gel: potential risk of…
specific-brands-of-carbomer-eye-gel-recall-of-aacarb-eye-gel-aacomer-eye-gel-and-puroptics-eye-gel-p Medical Device Alert
24 Nov 2023 MHRA
E-cigarette use or vaping: reminder to remain vigilant for suspected adverse reactions and safety concerns and report t…
e-cigarette-use-or-vaping-reminder-to-remain-vigilant-for-suspected-adverse-reactions-and-safety-con Drug Safety
23 Nov 2023 MHRA
Letters and medicine recalls sent to healthcare professionals in October 2023
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-october-2023 Drug Safety
23 Nov 2023 MHRA
Nirmatrelvir, ritonavir (Paxlovid▼): be alert to the risk of drug interactions with ritonavir
nirmatrelvir-ritonavir-paxlovidv-be-alert-to-the-risk-of-drug-interactions-with-ritonavir Drug Safety
23 Nov 2023 MHRA
Ozempic▼(semaglutide) and Saxenda (liraglutide): vigilance required due to potentially harmful falsified products
ozempicv-semaglutide-and-saxenda-liraglutide-vigilance-required-due-to-potentially-harmful-falsified Drug Safety
23 Nov 2023 MHRA
Field Safety Notices: 6 to 10 November 2023
field-safety-notices-6-to-10-november-2023 Medical Device Alert
17 Nov 2023 MHRA
Isotretinoin (Roaccutane▼): introduction of new safety measures, including additional oversight of the initiation of tr…
isotretinoin-roaccutanev-introduction-of-new-safety-measures-including-additional-oversight-of-the-i Drug Safety
31 Oct 2023 MHRA
Letters and medicine recalls sent to healthcare professionals in September 2023
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-september-2023 Drug Safety
31 Oct 2023 MHRA
MedSafetyWeek November 2023: your Yellow Card report helps to improve patient safety
medsafetyweek-november-2023-your-yellow-card-report-helps-to-improve-patient-safety Drug Safety
31 Oct 2023 MHRA
Valproate: dispense full packs of valproate-containing medicines
valproate-dispense-full-packs-of-valproate-containing-medicines Drug Safety
31 Oct 2023 MHRA
Fluoroquinolone antibiotics: suicidal thoughts and behaviour
fluoroquinolone-antibiotics-suicidal-thoughts-and-behaviour Drug Safety
26 Sep 2023 MHRA
Letters and medicine recalls sent to healthcare professionals in August 2023
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-august-2023 Drug Safety
26 Sep 2023 MHRA
Statins: very infrequent reports of myasthenia gravis
statins-very-infrequent-reports-of-myasthenia-gravis Drug Safety
26 Sep 2023 MHRA
Field Safety Notices: 4 to 8 September 2023
field-safety-notices-4-to-8-september-2023 Medical Device Alert
12 Sep 2023 MHRA
Class 4 Medicines Defect Information: Colgate-Palmolive (U.K.) Limited, Duraphat 5000ppm Fluoride Toothpaste (51g), EL …
class-4-medicines-defect-information-colgate-palmolive-uk-limited-duraphat-5000ppm-fluoride-toothpas Medical Device Alert
07 Sep 2023 MHRA
Valproate: re-analysis of study on risks in children of men taking valproate
valproate-re-analysis-of-study-on-risks-in-children-of-men-taking-valproate Drug Safety
30 Aug 2023 MHRA
Fluoroquinolone antibiotics: reminder of the risk of disabling and potentially long-lasting or irreversible side effects
fluoroquinolone-antibiotics-reminder-of-the-risk-of-disabling-and-potentially-long-lasting-or-irreve Drug Safety
30 Aug 2023 MHRA
Field Safety Notices (FSNs) from 21 to 25 August 2023
field-safety-notices-fsns-from-21-to-25-august-2023 Medical Device Alert
30 Aug 2023 MHRA
Methotrexate: advise patients to take precautions in the sun to avoid photosensitivity reactions
methotrexate-advise-patients-to-take-precautions-in-the-sun-to-avoid-photosensitivity-reactions Drug Safety
30 Aug 2023 MHRA
National Patient Safety Alert: Medical beds, trolleys, bed rails, bed grab handles and lateral turning devices: risk of…
national-patient-safety-alert-medical-beds-trolleys-bed-rails-bed-grab-handles-and-lateral-turning-d Medical Device Alert
30 Aug 2023 MHRA
Letters and medicine recalls sent to healthcare professionals in July 2023
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-july-2023 Drug Safety
30 Aug 2023 MHRA
Class 4 Medicines Defect Information: Galderma (U.K.) Limited, Loceryl 5% w/v Medicated Nail Lacquer (5.0 ml), EL (23)A…
class-4-medicines-defect-information-galderma-uk-limited-loceryl-5-percent-w-slash-v-medicated-nail- Medical Device Alert
29 Aug 2023 MHRA
Hyoscine hydrobromide patches (Scopoderm 1.5mg Patch or Scopoderm TTS Patch): risk of anticholinergic side effects, inc…
hyoscine-hydrobromide-patches-scopoderm-1-dot-5mg-patch-or-scopoderm-tts-patch-risk-of-anticholinerg Drug Safety
24 Jul 2023 MHRA
Codeine linctus: public consultation on the proposal to reclassify to a prescription-only medicine
codeine-linctus-public-consultation-on-the-proposal-to-reclassify-to-a-prescription-only-medicine Drug Safety
24 Jul 2023 MHRA
Letters and medicine recalls sent to healthcare professionals in June 2023
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-june-2023 Drug Safety
24 Jul 2023 MHRA
Field Safety Notices: 26 to 30 June 2023
field-safety-notices-26-to-30-june-2023 Medical Device Alert
05 Jul 2023 MHRA
Field Safety Notices (FSNs) from 19 to 23 June 2023
field-safety-notices-fsns-from-19-to-23-june-2023 Medical Device Alert
28 Jun 2023 MHRA
Calcium chloride, calcium gluconate: potential risk of underdosing with calcium gluconate in severe hyperkalaemia
calcium-chloride-calcium-gluconate-potential-risk-of-underdosing-with-calcium-gluconate-in-severe-hy Drug Safety
27 Jun 2023 MHRA
Letters and medicine recalls sent to healthcare professionals in May 2023
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-may-2023 Drug Safety
27 Jun 2023 MHRA
Adrenaline auto-injectors (AAIs): new guidance and resources for safe use
adrenaline-auto-injectors-aais-new-guidance-and-resources-for-safe-use Drug Safety
27 Jun 2023 MHRA
Non-steroidal anti-inflammatory drugs (NSAIDs): potential risks following prolonged use after 20 weeks of pregnancy
non-steroidal-anti-inflammatory-drugs-nsaids-potential-risks-following-prolonged-use-after-20-weeks- Drug Safety
27 Jun 2023 MHRA
Class 3 Medicines Recall: Tricodent Limited (supplier), Medical Oxygen B.P (MEDIGAS OXYGEN B.P), EL (23)A/20
class-3-medicines-recall-tricodent-limited-supplier-medical-oxygen-bp-medigas-oxygen-bp-el-23-a-slas Medical Device Alert
06 Jun 2023 MHRA
Field Safety Notices (FSNs) from 22 to 26 May 2023
list-of-field-safety-notices-fsns-from-22-to-26-may-2023 Medical Device Alert
06 Jun 2023 MHRA
Direct-acting oral anticoagulants (DOACs): paediatric formulations; reminder of dose adjustments in patients with renal…
direct-acting-oral-anticoagulants-doacs-paediatric-formulations-reminder-of-dose-adjustments-in-pati Drug Safety
25 May 2023 MHRA
Febuxostat: updated advice for the treatment of patients with a history of major cardiovascular disease
febuxostat-updated-advice-for-the-treatment-of-patients-with-a-history-of-major-cardiovascular-disea Drug Safety
25 May 2023 MHRA
Letters and medicine recalls sent to healthcare professionals in April 2023
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-april-2023 Drug Safety
25 May 2023 MHRA
Glucose solutions: recommendations to minimise the risks associated with the accidental use of glucose solutions instea…
glucose-solutions-recommendations-to-minimise-the-risks-associated-with-the-accidental-use-of-glucos Drug Safety
25 May 2023 MHRA
Field Safety Notices: 8 to 12 May 2023
field-safety-notices-8-to-12-may-2023 Medical Device Alert
16 May 2023 MHRA
Letters and medicine recalls sent to healthcare professionals in March 2023
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-march-2023 Drug Safety
26 Apr 2023 MHRA
Janus kinase (JAK) inhibitors: new measures to reduce risks of major cardiovascular events, malignancy, venous thromboe…
janus-kinase-jak-inhibitors-new-measures-to-reduce-risks-of-major-cardiovascular-events-malignancy-v Drug Safety
26 Apr 2023 MHRA
Nitrofurantoin: reminder of the risks of pulmonary and hepatic adverse drug reactions
nitrofurantoin-reminder-of-the-risks-of-pulmonary-and-hepatic-adverse-drug-reactions Drug Safety
26 Apr 2023 MHRA
Isotretinoin (Roaccutane▼): new safety measures to be introduced in the coming months, including additional oversight o…
isotretinoin-roaccutanev-new-safety-measures-to-be-introduced-in-the-coming-months-including-additio Drug Safety
26 Apr 2023 MHRA
Field Safety Notices: 27 to 31 March 2023
field-safety-notices-27-to-31-march-2023 Medical Device Alert
04 Apr 2023 MHRA
Terlipressin: new recommendations to reduce risks of respiratory failure and septic shock in patients with type 1 hepat…
terlipressin-new-recommendations-to-reduce-risks-of-respiratory-failure-and-septic-shock-in-patients Drug Safety
23 Mar 2023 MHRA