Theresa Thompson
PFD Report
Historic (No Identified Response)
Ref: 2017-0110
Coroner's Concerns (AI summary)
A post-splenectomy patient died from Streptococcus pneumonia due to lack of lifelong antibiotic prophylaxis and vaccination. Mixed messages about antibiotic use may deter patients from accepting crucial preventative treatments.
View full coroner's concerns
At the inquest;, the pathologist advised that Streptococcus pneumonia infections were typical for patients having undergone splenectomy: The spleen was an important immune defence organ for this type of bacteriae. Usually patients were given a vaccination to prevent this type of disease and life-time antibiotic prophylaxis. Both the Pathologist and Treating clinician at the time of death, expressed concerns to the inquest that Mrs Thompson was not on prophylaxis antibiotics and that she had no antibiotic prophylaxis cover for her recent procedure especially as the Streptococcus infection was Serum type 6C for which there was no currently available pneumococcal vaccines (Reference report from Public Health England, Colindale The Respiratory and Vaccine Preventable Bacteria Reference Unit I(RVPBRU): The GP gave evidence that Mrs Thompson had been advised about inoculation and taking life-long antibiotic prophylaxis but at some point had declined (although there were no written records to support his evidence in her medical note). There was no evidence that she was advised or prescribed antibiotics prior to or after her Ventriculo-Peritoneal Shunt procedure in August 2016 at Kings College Hospital. The family acknowledged that a number of the family had had a splenectomy due to familial Acholuric Jaundice but they were unsure that the family members appreciated the necessity for inoculation or prophylaxis antibiotics. were concerned that there were mixed messages given out by the Health Agencies about the use of antibiotics and the need to not overuse antibiotics and this had led to them not being inoculated or accepting life time prophylaxis antibiotics or the necessity of cover during medical procedures (f had been advised at all):
Sent To
- Public Health England
Response Status
Linked responses
0 of 1
56-Day Deadline
12 Jul 2017
About PFD responses
Organisations named in PFD reports must respond within 56 days explaining what actions they are taking.
Source: Courts and Tribunals Judiciary
Report Sections
Investigation and Inquest
Theresa Mary Thompson died 0n the 9"h October 2016 at the Royal Cornwall Hospital; Treliske, Truro while on holiday in Cornwall: An inquest was opened on the 14" October and concluded at Truro Municipal Buildings, Truro on 29th March 2017 with a conclusion of Natural Causes
Circumstances of the Death
Theresa Thompson underwent a Splenectomy when she was child in 1958 because of familial Acholuric Jaundice. Following the procedure she was advised on the need for indefinite prophylaxis with antibiotics t0 redress the risk of infection due to the reduction in efficiency of her immune system following the removal of the spleen: Mrs Thompson at some point declined antibiotics. In March 2013 she underwent ventriculo-peritoneal shunt: She developed sigmoid perforation and peritonitis in June 2013 and the infected ventriculo-peritoneal shunt was removed in Kings College Hospital, London: A new ventriculo-peritoneal shunt was re-inserted at Kings College Hospital, London on 8th August 2016 without prophylaxis antibiotics. She went on holiday to Cornwall and whilst on holiday she was admitted to the Royal Cornwall Hospital, Treliske, Truro on 8th October 2016 with sepsis from a Streptococcus pneumonia infection from which she died on gth October 2016. A post mortem was carried out and the cause of death was established as Ia Multi-organ failure 1b Sepsis Ic Streptococcus Pneumonia Il Ventriculo-Peritoneal Shunt for Normal Pressure Hydrocephalus, Previous bowel Perforation in 2013 with peritonitis, Splenectomy as child.
Action Should Be Taken
In my opinion action should be taken to prevent future deaths and believe you [ANDIOR your organisation] have the power to take such action. To ensure that there is clear medical advice provided to Health Agencies and professionals and patients as to actions to reduced risk of infection in cases where a patient's immune system may be compromised such as after a splenectomy, radiotherapy and the recommended risk reductions treatment such as prophylaxis antibiotics, inoculation.
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Data sourced from Courts and Tribunals Judiciary under the Open Government Licence.