Moses McDonald

PFD Report Partially Responded Ref: 2014-0524
Date of Report 2 December 2014
Coroner Lorna Tagliavini
Response Deadline est. 27 January 2015
Coroner's Concerns (AI summary)
The Clozapine clinic failed to conduct mandatory and regular glucose testing for patients receiving antipsychotic medication, posing a significant safety concern.
View full coroner's concerns
am aware of the steps that have already been taken to remedy area of concern in the Level One Investigation Report dated 15 August 2013 (draft) . However; this does not address: (1) The lack of mandatory and regular glucose testing while on antipsychotic medication by the Clozapine clinic.
Responses
South London Maudsley NHS Trust NHS / Health Body
2 Dec 2014
Action Taken
The Trust updated its physical healthcare policy to outline the responsibility of clinical staff to address patient's physical health needs and made it mandatory that all patients prescribed anti-psychotic medication should have a physical health check. The Trust will conduct a full review of the Clozapine clinics across the 4 boroughs within the next 6 months. (AI summary)
View full response
Dear Ms Tagliavini, Re Moses Andrew Arthur McDonald, Died 2"d April 2013, Case Ref: 883-2013 write in response to the Regulation 28 Report (o Prevent Future Deaths dated 2nd December 2014, which you sent following the Inquest into the death of Mr McDonald; In the report, you raised concerns relating to the lack of mandatory and regular glucose while on antipsychotic medication by the Clozapine clinic. My response and details of actions taken by the Trust are listed below. Glucose Testing for Patients Prescribed Anti-Psychotic Medication The current physical healthcare policy has recently been updated and outlines the responsibility of each member of clinical staff to address the physical health needs of all patients , The Trust publishes the Maudsley Prescribing Guidelines, which is used throughout the UK and internationally as guidance for prescribers. The physical healthcare policy includes reference to these guidelines for those patients who are prescribed Clozapine. Ideal monitoring would include a fasting blood glucose 0 glucose tolerance test afler a month; then every 4-6 months The recommended minimum monitoring is a urine glucose and random blood glucose before Clozapine is started, and repeated every 12 months, with regular monitoring of symptoms of fatigue, thirst, polyuria and candida infection; The Trust considers this monitoring a8 essential for patients on Clozapine. The policy also outlines the expectation that all patients prescribed anti LTagliavini Ref: 883+2043 MAA McD - 30.0L.15 Www,slam nhs uk 30"h testing

psychotic medication, which has the potential to impact o their physical health, should have a physical health care plan, In order to monitor compliance with the Maudsley Prescribing Guidelines, specifically relating to the physical health monitoring recommendations the Trust pharmacy team carry out regular audits and feedback to clinical services. Specifically within the Adult Mental Health pathway (AMH) the Trust provides training for clinical staff on medication management, Trainers have recently incorporated specific training for staff 0 Clozapine management covering issues relating to Trust policy and practice guidance. All Promoting Recovery teams have now identified physical healthcare leads whose remit include improving and maintaining standards and ensuring physical healthcare audits are completed and acted upon routinely. There are robust team processes in place in all tearns across the AMH pathway which includes daily planning meetings, clinical formation meetings and monthly clinical supervision where it is expected that clinical staff discuss, review and raise concerns about any patient who may be experiencing adverse effects from their medication including Clozapine. In addition in order to Iearn lessons from previous incidents clinical staff now receives regular feedback from the monthly learning lessons forums. These forums have representation fiom all pathways boroughs Function of the Clozapine Clinic The Trust, having reviewed the situation, has found that Clozapine clinics across the Trust operate differently in each Borough and there is a lack of clarity and consistency in relation to operational processes, resources, management responsibilities and function of these clinics In order to improve consistency of care provision and clarity of roles and responsibilities of physical health monitoring for patients attending the clinic the following actions will be taken within the next 6 months_ The Trust will carry ut a full revicw of the Clozapine clinics across the 4 boroughs with the aim of: Reviewing the existing operational processes, resources, management responsibilities and function of the Clozapine clinics in each borough Croydon; Lewisham; Southwark and Lambeth Determining the core finction of these clinics Clarifying the management roles, responsibilities and reporting structures within each clinic. Setting core standards of practice across all 4 boroughs Progress will be monitored and reported through the Trust Physical Healthcare committee and issues escalated as necessary to the Trust Quality Sub Committee. LTagliavini - Ref: 883-2013 MAA McD - 30.01.15

and

that this letter addresses the issues that You have raised and I would like to thank you bringing yOur concerns to my attention;
Sent To
  • Russell-Cooke solicitors
  • South London and Maudsley NHS Foundation Trust
Response Status
Linked responses 1 of 2
56-Day Deadline 27 Jan 2015
About PFD responses

Organisations named in PFD reports must respond within 56 days explaining what actions they are taking.

Source: Courts and Tribunals Judiciary

Report Sections
Investigation and Inquest
On 3 April 2013 commenced an investigation into the death of Moses Andrew Arthur McDonald aged 30 years The investigation concluded at the end of the inquest on 27 November 2014. The conclusion of the inquest was: "The deceased died as a result of a rare but well-known complication associated with the anti-psychotic medication Clozapine contributed to by a lack of regular glucose testing: The case of death was given by the pathologist as: Ia. Aspiration of stomach content 1b. Diabetic ketoacidosis
Circumstances of the Death
Mr McDonald had long been diagnosed with Paranoid Schizophrenia In June 2012 he was prescribed Clozapine in tablet form 150 mg BD and was therefore required to attend for regular blood testing to monitor his white cell count. Mr McDonald regularly attended for these mandatory blood tests and nothing untoward was found. However, his first and last glucose test in May 2012 was recorded at 7.4 and thereafter he was not re-tested for his glucose levels either by the Clozapine clinic or by his GP (having missed his last annual health check-up in February 2013). In March 2013 Mr McDonald complained of frequent urination and extreme thirst whilst on holiday and after his return. On 2 April 2013 Mr McDonald was found deceased at his home address, not having undergone any glucose testing since 2012 May
Action Should Be Taken
In my opinion action should be taken to prevent future deaths and believe your organisation have the power to take such action:
Related Inquiry Recommendations

Public inquiry recommendations addressing similar themes

Transfusion Committees and Tranexamic Acid - England
Infected Blood Inquiry
High-risk medication monitoring
Tranexamic Acid - Scotland, Wales and NI
Infected Blood Inquiry
High-risk medication monitoring
Medicines administration
Mid Staffs Inquiry
Unsafe medication management

Data sourced from Courts and Tribunals Judiciary under the Open Government Licence.