MHRA Drug & Device Safety Alerts

Safety alerts, recalls, and field safety notices from the Medicines and Healthcare products Regulatory Agency — covering drug safety updates, medical device alerts, and class recalls.

514
Total Alerts
250
Drug Safety Updates
264
Device Alerts

Alerts by Type

Key Insights

514 MHRA alerts tracked. 250 Drug Safety Updates. 264 Medical Device Alerts.

MHRA alerts link to NHS trusts and healthcare bodies — cross-reference with responsible body scorecard pages to surface patterns between safety alert volumes and inquiry recommendation delivery.

Showing 514 alerts

Letters and medicine recalls sent to healthcare professionals in April 2022
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-april-2022 Drug Safety
17 May 2022 MHRA
Field Safety Notices: 25 to 29 April 2022
field-safety-notices-25-to-29-april-2022 Medical Device Alert
03 May 2022 MHRA
Pregabalin (Lyrica): findings of safety study on risks during pregnancy
pregabalin-lyrica-findings-of-safety-study-on-risks-during-pregnancy Drug Safety
19 Apr 2022 MHRA
Letters and medicine recalls sent to healthcare professionals in March 2022
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-march-2022 Drug Safety
19 Apr 2022 MHRA
COVID-19 vaccines and medicines: updates for April 2022
covid-19-vaccines-and-medicines-updates-for-april-2022 Drug Safety
19 Apr 2022 MHRA
Field Safety Notices: 4 to 8 April 2022
field-safety-notices-4-to-8-april-2022 Medical Device Alert
11 Apr 2022 MHRA
Field Safety Notices: 28 March to 1 April 2022
field-safety-notices-28-march-to-1-april-2022 Medical Device Alert
04 Apr 2022 MHRA
Field Safety Notices: 21 to 25 March 2022
field-safety-notices-21-to-25-march-2022 Medical Device Alert
28 Mar 2022 MHRA
Metformin in pregnancy: study shows no safety concerns
metformin-in-pregnancy-study-shows-no-safety-concerns Drug Safety
15 Mar 2022 MHRA
Cladribine (Mavenclad): new advice to minimise risk of serious liver injury
cladribine-mavenclad-new-advice-to-minimise-risk-of-serious-liver-injury Drug Safety
15 Mar 2022 MHRA
Field Safety Notices: 7 to 11 March 2022
field-safety-notices-7-to-11-march-2022 Medical Device Alert
15 Mar 2022 MHRA
COVID-19 vaccines and medicines: updates for March 2022
covid-19-vaccines-and-medicines-updates-for-march-2022 Drug Safety
15 Mar 2022 MHRA
Amiodarone (Cordarone X): reminder of risks of treatment and need for patient monitoring and supervision
amiodarone-cordarone-x-reminder-of-risks-of-treatment-and-need-for-patient-monitoring-and-supervisio Drug Safety
15 Mar 2022 MHRA
Letters and medicine recalls sent to healthcare professionals in February 2022
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-february-2022 Drug Safety
15 Mar 2022 MHRA
Field Safety Notices: 14 to 18 February 2022
field-safety-notices-14-to-18-february-2022 Medical Device Alert
22 Feb 2022 MHRA
COVID-19 vaccines and medicines: updates for February 2022
covid-19-vaccines-and-medicines-updates-for-february-2022 Drug Safety
15 Feb 2022 MHRA
COVID-19 antivirals: reporting to the UK COVID-19 Antivirals Pregnancy Registry
covid-19-antivirals-reporting-to-the-uk-covid-19-antivirals-pregnancy-registry Drug Safety
15 Feb 2022 MHRA
Letters and medicine recalls sent to healthcare professionals in January 2022
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-january-2022 Drug Safety
15 Feb 2022 MHRA
Hydroxychloroquine, chloroquine: increased risk of cardiovascular events when used with macrolide antibiotics; reminder…
hydroxychloroquine-chloroquine-increased-risk-of-cardiovascular-events-when-used-with-macrolide-anti Drug Safety
15 Feb 2022 MHRA
Ivacaftor, tezacaftor, elexacaftor (Kaftrio▼) in combination with ivacaftor (Kalydeco): risk of serious liver injury; u…
ivacaftor-tezacaftor-elexacaftor-kaftriov-in-combination-with-ivacaftor-kalydeco-risk-of-serious-liv Drug Safety
15 Feb 2022 MHRA
COVID-19 vaccines and medicines: updates for January 2022
covid-19-vaccines-and-medicines-updates-for-january-2022 Drug Safety
18 Jan 2022 MHRA
Letters and medicine recalls sent to healthcare professionals in December 2021
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-december-2021 Drug Safety
18 Jan 2022 MHRA
Brolucizumab (Beovu▼): risk of intraocular inflammation and retinal vascular occlusion increased with short dosing inte…
brolucizumab-beovuv-risk-of-intraocular-inflammation-and-retinal-vascular-occlusion-increased-with-s Drug Safety
18 Jan 2022 MHRA
Paclitaxel formulations (conventional and nab-paclitaxel): caution required due to potential for medication error
paclitaxel-formulations-conventional-and-nab-paclitaxel-caution-required-due-to-potential-for-medica Drug Safety
18 Jan 2022 MHRA
Field Safety Notices: 20 to 24 December 2021
field-safety-notices-20-to-24-december-2021 Medical Device Alert
24 Dec 2021 MHRA
Field Safety Notices: 6 to 10 December 2021
field-safety-notices-6-to-10-december-2021 Medical Device Alert
13 Dec 2021 MHRA
Haloperidol (Haldol): reminder of risks when used in elderly patients for the acute treatment of delirium
haloperidol-haldol-reminder-of-risks-when-used-in-elderly-patients-for-the-acute-treatment-of-deliri Drug Safety
10 Dec 2021 MHRA
COVID-19 vaccines and medicines: updates for December 2021
covid-19-vaccines-and-medicines-updates-for-december-2021 Drug Safety
10 Dec 2021 MHRA
Venetoclax (Venclyxto▼): updated recommendations on tumour lysis syndrome (TLS)
venetoclax-venclyxtov-updated-recommendations-on-tumour-lysis-syndrome-tls Drug Safety
10 Dec 2021 MHRA
Dapagliflozin (Forxiga): no longer authorised for treatment of type 1 diabetes mellitus
dapagliflozin-forxiga-no-longer-authorised-for-treatment-of-type-1-diabetes-mellitus Drug Safety
10 Dec 2021 MHRA
Letters and medicine recalls sent to healthcare professionals in November 2021
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-november-2021 Drug Safety
10 Dec 2021 MHRA
Yellow fever vaccine (Stamaril): new pre-vaccination checklist
yellow-fever-vaccine-stamaril-new-pre-vaccination-checklist Drug Safety
16 Nov 2021 MHRA
Adrenaline auto-injectors: reminder for prescribers to support safe and effective use
adrenaline-auto-injectors-reminder-for-prescribers-to-support-safe-and-effective-use Drug Safety
16 Nov 2021 MHRA
Letters and medicine recalls sent to healthcare professionals in October 2021
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-october-2021 Drug Safety
16 Nov 2021 MHRA
COVID-19 vaccines and medicines: updates for November 2021
covid-19-vaccines-and-medicines-updates-for-november-2021 Drug Safety
16 Nov 2021 MHRA
Medical device alerts archived in November 2021
medical-device-alerts-archived-in-november-2021 Medical Device Alert
09 Nov 2021 MHRA
Field Safety Notices: 25 to 29 October 2021
field-safety-notices-25-to-29-october-2021 Medical Device Alert
01 Nov 2021 MHRA
Medical device alerts archived in October 2021
medical-device-alerts-archived-in-october-2021 Medical Device Alert
07 Oct 2021 MHRA
COVID-19 vaccines: updates for October 2021
covid-19-vaccines-updates-for-october-2021 Drug Safety
06 Oct 2021 MHRA
Tofacitinib (Xeljanz▼): new measures to minimise risk of major adverse cardiovascular events and malignancies
tofacitinib-xeljanzv-new-measures-to-minimise-risk-of-major-adverse-cardiovascular-events-and-malign Drug Safety
06 Oct 2021 MHRA
Letters and medicine recalls sent to healthcare professionals in September 2021
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-september-2021 Drug Safety
06 Oct 2021 MHRA
Chloral hydrate, cloral betaine (Welldorm): restriction of paediatric indication
chloral-hydrate-cloral-betaine-welldorm-restriction-of-paediatric-indication Drug Safety
06 Oct 2021 MHRA
MedSafetyWeek November 2021: support the safety of vaccines
medsafetyweek-november-2021-support-the-safety-of-vaccines Drug Safety
06 Oct 2021 MHRA
Field Safety Notices: 27 September to 01 October 2021
field-safety-notices-27-september-to-01-october-2021 Medical Device Alert
04 Oct 2021 MHRA
Class 2 Medicines Recall: Accord-UK Ltd (Trading style: NorthStar), LEVOTHYROXINE TABLETS BP 50 micrograms EL (21)A/23
class-2-medicines-recall-accord-uk-ltd-trading-style-northstar-levothyroxine-tablets-bp-50-microgram Medical Device Alert
27 Sep 2021 MHRA
Letters and medicine recalls sent to healthcare professionals in August 2021
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-august-2021 Drug Safety
15 Sep 2021 MHRA
COVID-19 vaccines and medicines: updates for September 2021
covid-19-vaccines-and-medicines-updates-for-september-2021 Drug Safety
15 Sep 2021 MHRA
Topical corticosteroids: information on the risk of topical steroid withdrawal reactions
topical-corticosteroids-information-on-the-risk-of-topical-steroid-withdrawal-reactions Drug Safety
15 Sep 2021 MHRA
COVID-19 vaccines: updates for August 2021
covid-19-vaccines-updates-for-august-2021 Drug Safety
16 Aug 2021 MHRA
Letters and medicine recalls sent to healthcare professionals in July 2021
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-july-2021 Drug Safety
16 Aug 2021 MHRA