MHRA Drug & Device Safety Alerts

Safety alerts, recalls, and field safety notices from the Medicines and Healthcare products Regulatory Agency — covering drug safety updates, medical device alerts, and class recalls.

514
Total Alerts
250
Drug Safety Updates
264
Device Alerts

Alerts by Type

Key Insights

514 MHRA alerts tracked. 250 Drug Safety Updates. 264 Medical Device Alerts.

MHRA alerts link to NHS trusts and healthcare bodies — cross-reference with responsible body scorecard pages to surface patterns between safety alert volumes and inquiry recommendation delivery.

Showing 514 alerts

Field Safety Notices: 2 to 6 August 2021
field-safety-notices-2-to-6-august-2021 Medical Device Alert
09 Aug 2021 MHRA
Field Safety Notices: 19 to 23 July 2021
field-safety-notices-19-to-23-july-2021 Medical Device Alert
26 Jul 2021 MHRA
Letters and medicine recalls sent to healthcare professionals in June 2021
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-june-2021 Drug Safety
07 Jul 2021 MHRA
Herbal and homeopathic medicines: reminder to be vigilant for suspected adverse reactions and to report them to the Yel…
herbal-and-homeopathic-medicines-reminder-to-be-vigilant-for-suspected-adverse-reactions-and-to-repo Drug Safety
07 Jul 2021 MHRA
Oral retinoid medicines (isotretinoin▼, alitretinoin▼, and acitretin▼): temporary monitoring advice during coronavirus …
oral-retinoid-medicines-isotretinoinv-alitretinoinv-and-acitretinv-temporary-monitoring-advice-durin Drug Safety
07 Jul 2021 MHRA
Chloramphenicol eye drops containing borax or boric acid buffers: use in children younger than 2 years
chloramphenicol-eye-drops-containing-borax-or-boric-acid-buffers-use-in-children-younger-than-2-year Drug Safety
07 Jul 2021 MHRA
COVID-19 vaccines: updates for July 2021
covid-19-vaccines-updates-for-july-2021 Drug Safety
07 Jul 2021 MHRA
National Patient Safety Alert: Philips ventilator, CPAP and BiPAP devices: Potential for patient harm due to inhalation…
national-patient-safety-alert-philips-ventilator-cpap-and-bipap-devices-potential-for-patient-harm-d Medical Device Alert
23 Jun 2021 MHRA
Field Safety Notices: 14 to 18 June 2021
field-safety-notices-14-to-18-june-2021 Medical Device Alert
21 Jun 2021 MHRA
COVID-19 vaccines: updates for June 2021
covid-19-vaccines-updates-for-june-2021 Drug Safety
17 Jun 2021 MHRA
CDK4/6 inhibitors (abemaciclib▼, palbociclib▼, ribociclib▼): reports of interstitial lung disease and pneumonitis, incl…
cdk4-slash-6-inhibitors-abemaciclibv-palbociclibv-ribociclibv-reports-of-interstitial-lung-disease-a Drug Safety
17 Jun 2021 MHRA
Letters and medicine recalls sent to healthcare professionals in May 2021
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-may-2021 Drug Safety
17 Jun 2021 MHRA
Atezolizumab (Tecentriq▼) and other immune-stimulatory anti-cancer drugs: risk of severe cutaneous adverse reactions (S…
atezolizumab-tecentriqv-and-other-immune-stimulatory-anti-cancer-drugs-risk-of-severe-cutaneous-adve Drug Safety
17 Jun 2021 MHRA
National Patient Safety Alert: Class 1 Medicines Recall Notification: Recall of Co-codamol 30/500 Effervescent Tablets,…
national-patient-safety-alert-class-1-medicines-recall-notification-recall-of-co-codamol-30-slash-50 Medical Device Alert
16 Jun 2021 MHRA
Field Safety Notices: 7 to 11 June 2021
field-safety-notices-7-to-11-june-2021 Medical Device Alert
14 Jun 2021 MHRA
Field Safety Notices: 31 May to 4 June 2021
field-safety-notices-31-may-to-4-june-2021 Medical Device Alert
07 Jun 2021 MHRA
Field Safety Notices: 17 to 21 May 2021
field-safety-notices-17-to-21-may-2021 Medical Device Alert
24 May 2021 MHRA
Emollients and risk of severe and fatal burns: new resources available
emollients-and-risk-of-severe-and-fatal-burns-new-resources-available Drug Safety
20 May 2021 MHRA
Letters and medicine recalls sent to healthcare professionals in April 2021
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-april-2021 Drug Safety
19 May 2021 MHRA
COVID-19 vaccines: updates for May 2021
covid-19-vaccines-updates-for-may-2021 Drug Safety
19 May 2021 MHRA
Levothyroxine: new prescribing advice for patients who experience symptoms on switching between different levothyroxine…
levothyroxine-new-prescribing-advice-for-patients-who-experience-symptoms-on-switching-between-diffe Drug Safety
19 May 2021 MHRA
Field Safety Notices: 10 to 14 May 2021
field-safety-notices-10-to-14-may-2021 Medical Device Alert
17 May 2021 MHRA
Field Safety Notices: 3 to 7 May 2021
field-safety-notices-03-to-07-may-2021 Medical Device Alert
10 May 2021 MHRA
Letters and medicine recalls sent to healthcare professionals in March 2021
letters-and-medicine-recalls-sent-to-healthcare-professionals-in-march-2021 Drug Safety
27 Apr 2021 MHRA
Polyethylene glycol (PEG) laxatives and starch-based thickeners: potential interactive effect when mixed, leading to an…
polyethylene-glycol-peg-laxatives-and-starch-based-thickeners-potential-interactive-effect-when-mixe Drug Safety
27 Apr 2021 MHRA
COVID-19 vaccines: updates for April 2021
covid-19-vaccines-updates-for-april-2021 Drug Safety
27 Apr 2021 MHRA
Bendamustine (Levact): increased risk of non-melanoma skin cancer and progressive multifocal encephalopathy (PML)
bendamustine-levact-increased-risk-of-non-melanoma-skin-cancer-and-progressive-multifocal-encephalop Drug Safety
24 Mar 2021 MHRA
COVID-19 vaccines and medicines: updates for March 2021
covid-19-vaccines-and-medicines-updates-for-march-2021 Drug Safety
24 Mar 2021 MHRA
Letters and drug alerts sent to healthcare professionals in February 2021
letters-and-drug-alerts-sent-to-healthcare-professionals-in-february-2021 Drug Safety
24 Mar 2021 MHRA
Field Safety Notices: 15 to 19 March 2021
field-safety-notices-15-to-19-march-2021 Medical Device Alert
22 Mar 2021 MHRA
Field Safety Notices: 1 to 5 March 2021
field-safety-notices-1-to-5-march-2021 Medical Device Alert
08 Mar 2021 MHRA
Changes to MHRA Drug alert titles and classification
changes-to-mhra-drug-alert-titles-and-categories Medical Device Alert
04 Mar 2021 MHRA
Field Safety Notices: 22 to 26 February 2021
field-safety-notices-22-to-26-february-2021 Medical Device Alert
01 Mar 2021 MHRA
Targeted letter: Implantable orthopaedic devices manufactured by Implants International Ltd trading as Xtremity Solutio…
targeted-letter-implantable-orthopaedic-devices-manufactured-by-implants-international-ltd-trading-a Medical Device Alert
26 Feb 2021 MHRA
Alkindi (hydrocortisone granules): risk of acute adrenal insufficiency in children when switching from hydrocortisone t…
alkindi-hydrocortisone-granules-risk-of-acute-adrenal-insufficiency-in-children-when-switching-from- Drug Safety
18 Feb 2021 MHRA
Pregabalin (Lyrica): reports of severe respiratory depression
pregabalin-lyrica-reports-of-severe-respiratory-depression Drug Safety
18 Feb 2021 MHRA
Ulipristal acetate 5mg (Esmya): further restrictions due to risk of serious liver injury
ulipristal-acetate-5mg-esmya-further-restrictions-due-to-risk-of-serious-liver-injury Drug Safety
18 Feb 2021 MHRA
COVID-19 vaccines and medicines: updates for February 2021
covid-19-vaccines-and-medicines-updates-for-february-2021 Drug Safety
18 Feb 2021 MHRA
Letters and drug alerts sent to healthcare professionals in January 2021
letters-and-drug-alerts-sent-to-healthcare-professionals-in-january-2021 Drug Safety
18 Feb 2021 MHRA
Medicines in pregnancy and breastfeeding: new initiative for consistent guidance; report on optimising data for medicin…
medicines-in-pregnancy-and-breastfeeding-new-initiative-for-consistent-guidance-report-on-optimising Drug Safety
18 Feb 2021 MHRA
Field Safety Notices: 8 to 12 February 2021
field-safety-notices-8-to-12-february-2021 Medical Device Alert
15 Feb 2021 MHRA
Field Safety Notices: 01 to 05 February 2021
field-safety-notices-01-to-05-february-2021 Medical Device Alert
08 Feb 2021 MHRA
Field Safety Notices: 18 to 22 January 2021
field-safety-notices-18-to-22-january-2021 Medical Device Alert
26 Jan 2021 MHRA
Aminoglycosides (gentamicin, amikacin, tobramycin, and neomycin): increased risk of deafness in patients with mitochond…
aminoglycosides-gentamicin-amikacin-tobramycin-and-neomycin-increased-risk-of-deafness-in-patients-w Drug Safety
07 Jan 2021 MHRA
Dimethyl fumarate (Tecfidera): updated advice on the risk of progressive multifocal leukoencephalopathy (PML) associate…
dimethyl-fumarate-tecfidera-updated-advice-on-the-risk-of-progressive-multifocal-leukoencephalopathy Drug Safety
07 Jan 2021 MHRA
SSRI/SNRI antidepressant medicines: small increased risk of postpartum haemorrhage when used in the month before delive…
ssri-slash-snri-antidepressant-medicines-small-increased-risk-of-postpartum-haemorrhage-when-used-in Drug Safety
07 Jan 2021 MHRA
Antiepileptic drugs in pregnancy: updated advice following comprehensive safety review
antiepileptic-drugs-in-pregnancy-updated-advice-following-comprehensive-safety-review Drug Safety
07 Jan 2021 MHRA
COVID-19 vaccines (Pfizer/BioNTech and COVID-19 Vaccine AstraZeneca): current advice
covid-19-vaccines-pfizer-slash-biontech-and-covid-19-vaccine-astrazeneca-current-advice Drug Safety
07 Jan 2021 MHRA
Letters and drug alerts sent to healthcare professionals in December 2020
letters-and-drug-alerts-sent-to-healthcare-professionals-in-december-2020 Drug Safety
07 Jan 2021 MHRA
Fingolimod (Gilenya▼): updated advice about the risks of serious liver injury and herpes meningoencephalitis
fingolimod-gilenyav-updated-advice-about-the-risks-of-serious-liver-injury-and-herpes-meningoencepha Drug Safety
07 Jan 2021 MHRA