NHS Patient Safety Alerts

39 National Patient Safety Alerts requiring NHS organisations to take specific actions to prevent serious harm or death. Source.

39
Total Alerts
40
Trusts Past Deadline

Compliance data: CAS snapshot 2 March 2026.

Alerts by Year

Key Findings

40 NHS trusts have outstanding non-compliance with patient safety alerts, totalling 60 open items. 33 alerts are past their completion deadline.
NatPSA/2023/016/DHSC
Inappropriate dosing risk when switching insulin degludec (Tresiba) products
Issued 8 December 2023 · Deadline: 22 December 2023 · DHSC
Past Deadline

Patients switched between Tresiba concentrations incorrectly advised on dosing, causing errors and hospitalisation.

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NatPSA/2023/015/UKHSA
Contamination of carbomer-containing lubricating eye products with Burkholderia cenocepacia
Issued 7 December 2023 · Deadline: 17 December 2023 · UKHSA
Past Deadline

Burkholderia cenocepacia outbreak linked to contaminated carbomer-containing eye products.

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NatPSA/2023/014/NHSPS
Identified safety risks with the Euroking maternity information system
Issued 7 December 2023 · Deadline: 7 June 2024 · NHS England Patient Safety

Euroking maternity IT system has data overwrite and forward-copy bugs. Providers must review and eliminate risks.

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NatPSA/2023/013/MHRA
Valproate: new regulatory measures for prescribing oversight
Issued 28 November 2023 · Deadline: 31 January 2024 · MHRA
Past Deadline

New valproate prescribing controls from January 2024. Must not start in patients under 55 unless two specialists approve.

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NatPSA/2023/012/DHSC
Shortage of verteporfin 15mg powder for solution for injection
Issued 28 September 2023 · DHSC

Supply shortage of verteporfin used in photodynamic therapy for wet age-related macular degeneration.

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NatPSA/2023/011/DHSC
Shortage of ADHD medications (methylphenidate, lisdexamfetamine, guanfacine)
Issued 27 September 2023 · Deadline: 11 October 2023 · DHSC
Past Deadline

Supply disruptions affecting multiple ADHD medications due to manufacturing issues and increased global demand.

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NatPSA/2023/010/MHRA
Medical beds, trolleys, bed rails: risk of death from entrapment or falls
Issued 30 August 2023 · Deadline: 1 March 2024 · MHRA

18 deaths and 54 serious injuries 2018-2022. Update policies, train staff, ensure risk assessments for all bed rail patients.

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NatPSA/2023/009/OHID
Potent synthetic opioids implicated in heroin overdoses and deaths
Issued 26 July 2023 · OHID

Potent synthetic opioids (nitazenes) found in heroin supply causing overdoses and deaths. Prepare for patients needing higher naloxone doses.

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NatPSA/2023/008/DHSC
Shortage of GLP-1 receptor agonists
Issued 18 July 2023 · Deadline: 18 October 2023 · DHSC
Past Deadline

Very limited supplies of all GLP-1 receptor agonists. Discourages off-label use for obesity; conserve stock for diabetes.

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NatPSA/2023/007/MHRA
Potential risk of underdosing with calcium gluconate in severe hyperkalaemia
Issued 27 June 2023 · Deadline: 1 December 2023 · MHRA
Past Deadline

Address medication errors in severe hyperkalaemia. 30ml of 10% calcium gluconate required for full dose.

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NatPSA/2023/006/DHSC
Shortage of pyridostigmine 60mg tablets
Issued 24 May 2023 · DHSC

Supply shortage of pyridostigmine 60mg tablets used for myasthenia gravis treatment.

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NatPSA/2023/005/MHRA
Removal of Philips V60 and V60 Plus ventilators from service: risk of unexpected shutdown
Issued 18 May 2023 · Deadline: 30 September 2023 · MHRA
Past Deadline

Permanently withdraw Philips V60 ventilators from clinical use due to risk of unexpected shutdown without warning alarm.

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NatPSA/2023/004/MHRA
Class 1 Medicines Recall: Emerade 500 and 300 microgram auto-injectors due to device failure
Issued 9 May 2023 · Deadline: 12 May 2023 · MHRA
Past Deadline

Urgent Class 1 recall of all Emerade adrenaline auto-injectors due to device failure risk. Prescribe alternative EpiPen or Jext.

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NatPSA/2023/003/MHRA
NIDEK EyeCee One preloaded Intraocular Lenses: risk of increased intraocular pressure
Issued 1 February 2023 · Deadline: 16 February 2023 · MHRA
Past Deadline

Identify patients who received these lenses since October 2022, cease use, quarantine stock, arrange IOP testing.

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NatPSA/2023/002/CMU
Supply of Licensed and Unlicensed Epidural Infusion Bags
Issued 23 January 2023 · DHSC

Supply disruptions affecting licensed and unlicensed epidural infusion bag products.

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NatPSA/2023/001/NHSPS
Use of oxygen cylinders where patients do not have access to medical gas pipeline systems
Issued 10 January 2023 · Deadline: 10 July 2023 · NHS England Patient Safety
Past Deadline

Healthcare organisations must review guidance on safe oxygen cylinder use and conduct risk assessments in escalation/transient care areas.

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Trusts with open alerts past deadline 2 March 2026 snapshot