NHS Patient Safety Alerts

39 National Patient Safety Alerts requiring NHS organisations to take specific actions to prevent serious harm or death. Source.

39
Total Alerts
40
Trusts Past Deadline

Compliance data: CAS snapshot 2 March 2026.

Alerts by Year

Key Findings

40 NHS trusts have outstanding non-compliance with patient safety alerts, totalling 60 open items. 33 alerts are past their completion deadline.
NatPSA/2024/013/DHSC
Shortage of Pancreatic enzyme replacement therapy (PERT) - Additional actions
Issued 18 December 2024 · Deadline: 31 January 2025 · DHSC

Supplements NatPSA/2024/007/DHSC. Continued limited Creon supplies through 2026.

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NatPSA/2024/012/DHSC
Shortage of Molybdenum-99/Technetium-99m generators
Issued 25 October 2024 · Deadline: 8 November 2024 · DHSC
Past Deadline

Shortage of Mo-99/Tc-99m generators used in nuclear medicine diagnostic imaging.

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NatPSA/2024/011/DHSC
Discontinuation of Kay-Cee-L (potassium chloride) syrup
Issued 21 October 2024 · Deadline: 31 October 2024 · DHSC
Past Deadline

Kay-Cee-L discontinuing late November 2024. Supersedes NatPSA/2024/008/DHSC.

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NatPSA/2024/010/NHSPS
Risk of oxytocin overdose during labour and childbirth
Issued 24 September 2024 · Deadline: 31 March 2025 · NHS England Patient Safety

Cease pre-preparing oxytocin infusions at ward level. Higher postnatal dose accidentally given before birth harms mother and infant.

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NatPSA/2024/009/DHSC
Shortage of Human Albumin 4.5% and 5% dose vials
Issued 30 July 2024 · Deadline: 7 August 2024 · DHSC
Past Deadline

Limited Human Albumin stock July-December 2024. Prioritise for critical patients.

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NatPSA/2024/008/DHSC
Shortage of Kay-Cee-L (potassium chloride) syrup
Issued 26 July 2024 · Deadline: 12 August 2024 · DHSC
Past Deadline

Impending Kay-Cee-L shortage from late September 2024. Superseded by NatPSA/2024/011/DHSC.

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NatPSA/2024/007/DHSC
Shortage of Pancreatic enzyme replacement therapy (PERT)
Issued 24 May 2024 · Deadline: 10 June 2024 · DHSC
Past Deadline

Limited Creon 10,000 and 25,000 capsule supplies with constraints until 2026.

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NatPSA/2024/006/DHSC
Shortage of Orencia ClickJect (abatacept) 125mg pre-filled pens
Issued 23 May 2024 · Deadline: 6 June 2024 · DHSC
Past Deadline

Supply shortage of Orencia ClickJect (abatacept) pre-filled pens for rheumatoid arthritis.

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NatPSA/2024/005/DHSC
Shortage of Erelzi (etanercept) 50mg pre-filled pen
Issued 3 May 2024 · Deadline: 10 May 2024 · DHSC
Past Deadline

Supply shortage of Erelzi (etanercept) pre-filled pens for autoimmune conditions.

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NatPSA/2024/004/MHRA
Reducing risks for transfusion-associated circulatory overload (TACO)
Issued 4 April 2024 · Deadline: 4 October 2024 · MHRA

TACO caused 111 deaths (39.2% of transfusion fatalities) 2010-2022. Implement risk assessments and staff training.

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NatPSA/2024/003/DHSC
Shortage of salbutamol nebuliser liquid unit dose vials
Issued 26 February 2024 · Deadline: 8 March 2024 · DHSC
Past Deadline

Supply shortage of salbutamol nebuliser liquid unit dose vials.

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NatPSA/2024/002/NHSPS
Transition to NRFit connectors for intrathecal and epidural procedures
Issued 31 January 2024 · Deadline: 31 January 2025 · NHS England Patient Safety

Replace Luer connectors with NRFit for intrathecal/epidural procedures to prevent fatal wrong-route administration.

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NatPSA/2024/001/DHSC
Shortage of GLP-1 receptor agonists (update)
Issued 3 January 2024 · Deadline: 28 March 2024 · DHSC
Past Deadline

GLP-1 RA supply not expected to normalise until at least end of 2024. Supersedes NatPSA/2023/008/DHSC.

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Trusts with open alerts past deadline 2 March 2026 snapshot